Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap
- Creator: Tu, Xiaofan , Kim, Richard Y. , Loering, Svenja , Nguyen, Duc H. , Nair, Prema Mono , Haw, Tatt Jhong , Alemao, Charlotte A. , Faiz, Alen , Tay, Hock L. , Wark, Peter A. B. , Knight, Darryl A. , Foster, Paul S. , Brown, Alexandra C. , Bosco, Anthony , Horvat, Jay C. , Hansbro, Philip M. , Donovan, Chantal , de Jong, Emma , Jones-Freeman, Bernadette , Ali, Md Khadem , Gomez, Henry M. , Budden, Kurtis F. , Starkey, Malcolm R. , Cameron, Guy J. M.
- Resource Type: journal article
- Date: 2022
A selective a7 nicotinic acetylcholine receptor agonist, PNU-282987, attenuates ILC2s activation and alternaria-induced airway inflammation
- Creator: Yuan, Fang , Jiang, Lili , Yang, Ming , Li, Fuguang , Li, Qianyang , Sokulsky, Leon , Wanyan, Yuanyuan , Wang, Lingli , Liu, Xiaojie , Zhou, Lujia , Tay, Hock L. , Zhang, Guojun
- Resource Type: journal article
- Date: 2021
T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet
- Creator: Barnes, Jessica L. , Plank, Maximilian W. , Hansbro, Philip M. , Keely, Simon , Belz, Gabrielle T. , Tay, Hock L. , Foster, Paul S. , Asquith, Kelly , Maltby, Steven , Sabino, Lorena R. , Kaiko, Gerard E. , Lochrin, Alyssa , Horvat, Jay C. , Mayall, Jemma R. , Kim, Richard Y.
- Resource Type: journal article
- Date: 2021
Uridine diphosphate-glucose/P2Y₁₄R axis is a nonchemokine pathway that selectively promotes eosinophil accumulation
- Creator: Foster, Paul S. , Tay, Hock L. , Hogan, Simon P.
- Resource Type: journal article
- Date: 2021
Biologics or immunotherapeutics for asthma?
- Creator: Tay, Hock L. , Foster, Paul S.
- Resource Type: journal article
- Date: 2020
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
- Creator: Ali, Md Khadem , Kim, Richard Y. , Donovan, Chantal , Pathinayake, Prabuddha S. , Carroll, Olivia R. , Trinder, Debbie , Tay, Hock L. , Badi, Yusef E. , Kermani, Nazanin Z. , Guo, Yi-Ke , Aryal, Ritambhara , Mumby, Sharon , Brown, Alexandra C. , Pavlidis, Stelios , Adcock, IM , Weaver, Jessica , Xenaki, D , Oliver, BG , Holliday, Elizabeth G. , Foster, Peter S. , Wark, Peter A. , Johnstone, DM , Milward, EA , Mayall, Jemma R. , Hansbro, Philip M. , Horvat, Jay C. , Karim, Rafia , Pinkerton, James W. , Liu, Gang , Martin, Kristy L. , Starkey, Malcolm R. , Pillar, Amber L.
- Resource Type: journal article
- Date: 2020
Lipopolysaccharide induces steroid-resistant exacerbations in a mouse model of allergic airway disease collectively through IL-13 and pulmonary macrophage activation
- Creator: Hadjigol, Sara , Netto, Keilah G. , Maltby, Steven , Tay, Hock L. , Nguyen, Thi H. , Hansbro, Nicole G. , Eyers, Fiona , Hansbro, Philip M. , Yang, Ming , Foster, Paul S.
- Resource Type: journal article
- Date: 2020
Identification of IFN-γ and IL-27 as critical regulators of respiratory syncytial virus-induced exacerbation of allergic airways disease in a mouse model
- Creator: Nguyen, Thi Hiep , Maltby, Steven , Tay, Hock L. , Eyers, Fiona , Foster, Paul S. , Yang, Ming
- Resource Type: journal article
- Date: 2018
IL-6 drives neutrophil-mediated pulmonary inflammation associated with bacteremia in murine models of colitis
- Creator: Mateer, Sean W. , Mathe, Andrea , Kim, Richard Y. , Minahan, Kyra , Walker, Marjorie M. , Callister, Robert C. , Foster, Paul S. , Horvat, Jay C. , Hansbro, Philip M. , Keely, Simon , Bruce, Jessica , Liu, Gang , Maltby, Steven , Fricker, Michael , Goggins, Bridie J. , Tay, Hock L. , Marks, Ellen , Burns, Grace
- Resource Type: journal article
- Date: 2018
Osteoblasts Are Rapidly Ablated by Virus-Induced Systemic Inflammation following Lymphocytic Choriomeningitis Virus or Pneumonia Virus of Mice Infection in Mice
- Creator: Maltby, Steven , Lochrin, Alyssa J. , Bartlett, Bianca , Tay, Hock L. , Weaver, Jessica , Poulton, Ingrid J. , Plank, Maximilian W. , Rosenberg, Helene F. , Sims, Natalie A. , Foster, Paul S.
- Resource Type: journal article
- Date: 2018
Modeling TH 2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma
- Creator: Foster, Paul S. , Maltby, Steven , Mattes, Joerg , Rosenberg, Helene F. , Tay, Hock L. , Hogan, Simon P. , Collison, Adam M. , Yang, Ming , Kaiko, Gerard E. , Hansbro, Philip M. , Kumar, Rakesh K.
- Resource Type: journal article
- Date: 2017
Mouse models of severe asthma: understanding the mechanisms of steroid resistance, tissue remodelling and disease exacerbation
- Creator: Maltby, Steven , Tay, Hock L. , Yang, Ming , Foster, Paul S.
- Resource Type: journal article
- Date: 2017
Th22 cells form a distinct Th lineage from Th17 cells in vitro with unique transcriptional properties and Tbet-dependent Th1 plasticity
- Creator: Plank, Maximilian W. , Kaiko, Gerard E. , Maltby, Steven , Weaver, Jessica , Tay, Hock L. , Shen, Wei , Wilson , Mark S. , Durum, Scott K. , Foster, Paul S.
- Resource Type: journal article
- Date: 2017
Identification of the microRNA networks contributing to macrophage differentiation and function
- Creator: Zhou, Hong , Zhang, Jie , Eyers, Fiona , Xiang, Yang , Herbert, Cristan , Tay, Hock L. , Foster, Paul S. , Yang, Ming
- Resource Type: journal article
- Date: 2016
MicroRNA-487b is a negative regulator of macrophage activation by targeting IL-33 production
- Creator: Xiang, Yang , Eyers, Fiona , Herbert, Cristan , Tay, Hock L. , Foster, Paul S. , Yang, Ming
- Resource Type: journal article
- Date: 2016
Targeting MicroRNA function in respiratory diseases: mini-review
- Creator: Maltby, Steven , Plank, Maximillian , Tay, Hock L. , Collison, Adam , Foster, Paul S.
- Resource Type: journal article
- Date: 2016
Antagonism of miR-328 increases the antimicrobial function of macrophages and neutrophils and rapid clearance of non-typeable Haemophilus Influenzae (NTHi) from infected lung
- Creator: Tay, Hock L. , Kaiko, Gerald E. , Foster, Paul S. , Plank, Maximilian , Li, JingJing , Maltby, Steven , Essilfie, Ama-Tawiah , Jarnicki, Andrew , Yang, Ming , Mattes, Joerg , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2015
MicroRNA expression is altered in an ovalbumin-induced asthma model and targeting miR-155 with antagomirs reveals cellular specificity
- Creator: Plank, Maximilian W. , Maltby, Steven , Tay, Hock L. , Stewart, Jessica , Eyers, Fiona , Hansbro, Philip M. , Foster, Paul S.
- Resource Type: journal article
- Date: 2015
MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity
- Creator: Li, Jing Jing , Tay, Hock L. , Mattes, Joerg , Foster, Paul S. , Yang, Ming , Maltby, Steven , Xiang, Yang , Eyers, Fiona , Hatchwell, Luke , Zhou, Hong , Toop, Hamish D. , Morris, Jonathan C. , Nair, Parameswaran
- Resource Type: journal article
- Date: 2015
MicroRNA: potential biomarkers and therapeutic targets for allergic asthma?
- Creator: Tay, Hock L. , Plank, Maximillan , Collison, Adam , Mattes, Joerg , Kumar, Rakesh K. , Foster, Paul S.
- Resource Type: journal article
- Date: 2014